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BACKGROUND AND OBJECTIVES:

Latest proof has steered that cannabis use precipitates cerebrovascular occasions. We investigated the connection between cannabis use dysfunction (CUD) and hospitalization for epilepsy.

METHODS:

Nationwide inpatient pattern (NIS) was analyzed from 2010 to 2014 for sufferers (age 15-54) with a main prognosis of epilepsy (N = 657 072) and comparability was made between sufferers with ICD-9 classification of CUD and with out CUD. We utilized logistic regression to check the affiliation (odds ratio [OR]) between CUD and epilepsy.

RESULTS:

The incidence of CUD in epilepsy sufferers was 5.77%, and sufferers with CUD had a threefold greater chance of emergency admissions. Sufferers with CUD had been youthful (25-34 years), male and African American. In regression evaluation, adjusted for confounders, cannabis (OR, 1.56), tobacco (OR, 1.20), and alcohol (OR, 1.63) use problems had been discovered to be related to greater odds of epilepsy hospitalization, however decrease odds with cocaine (OR, 0.953), amphetamine (OR, 0.893), and opioid (OR, 0.828) use problems.

CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE:

With the growing prevalence of medical marijuana legalization, there’s elevated use of medicinal marijuana. Research of cannabidiol and marijuana for epilepsy have been extremely publicized, resulting in its off-label use for therapy. There’s restricted proof to recommend that the cannabinoids can also induce a seizure. This research discovered that CUD is independently related to a 56% elevated chance of epilepsy hospitalization and this affiliation persists even after adjusting for different substance use problems and confounders. (Am J Addict 2019;1-9).

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